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KMID : 1161420210240111191
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Journal of Medicinal Food
2021 Volume.24 No. 11 p.1191 ~ p.1196
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Curcuma-Based Nutritional Supplement in Patients with Neovascular Age-Related Macular Degeneration
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Allegrini Davide
Raimondi Raffaele
Angi Martina
Ricciardelli Gabriella
Montericcio Alessio
Borgia Alfredo
Romano Mario R.
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Abstract
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To investigate effectiveness and safety of a curcumin-based nutritional supplement in neovascular age-related macular degeneration (AMD). We conducted a controlled retrospective study, reviewing the medical records of patients referred to the Eye Center, Humanitas Hospital, Bergamo due to neovascular AMD and treated with antivascular endothelial growth factor (VEGF) intravitreal injections (IVIs) and oral administration of a curcumin-based nutritional supplement vehiculated by enterosoma-I®. We retrospectively collected data of 18 naive patients who received IVI and daily oral nutritional supplement and 24 naive age-matched controls with the same diagnosis undergoing only IVI. All patients underwent a loading-phase of one-per-month IVI for 3 months and then received IVI pro re nata. Median best-corrected visual acuity was significantly improved in treated patients compared with controls (P??.05). The total number of injections (tIVI) was significantly (P?
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KEYWORD
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AMD, anti-VEGF, astaxanthin, curcumin, enterosoma, intravitreal injections
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